Diagnosis for Lyme Disease
Lyme disease is a
"clinical" diagnosis (like depression), which requires a knowledgeable “Lyme-literate”
doctor to piece together the
clues. Diagnostic tests are supposed to support a diagnosis
In early 2012 it was not possible to get a diffinitive diagnosis through a regular doctor. The
reason? The IDSA (Infectious Disease Society of America requires a two-tiered blood test for diagnosing Lyme
that according to the CDC routinely misses 50% or more of those who are infected.
However as of 8/1/2012,
there is a new test that is 94% accurate! This blood test will test
for multiple species of Borrelia, and verify any finding with DNA. The test was developed with the assistance of Dr.
Burrascano, but unfortunately it has been black balled by the state of New York and bad mouthed by the CDC. Dr.
Jemsek says in "Emmergence", the sequel to Under Our Skin, that it is the first time in history
that the CDC has put down a diagnostic tool - all the more concerning due to the desperate need for a
test that can accurately diagnose those caught in this raging epidemic.. See Advanced Laboratory Services Spirochete
If you can ask for a
test, the ITT/Cytokine test by Neurosciences called "My Lyme Immune ID"
test. Read about it here. Dr. Chitra
Bhakta describes applications of the MY Lyme Immune I.D. test in her practice below.
For the most detailed
information on how to diagnose Lyme disease see: Dr. Burrascano's Lyme Treatment Guidelines. These were updated in 2008
however, you must have Adobe free reader installed to download the file. You can download your free Adobe reader here. Another
excellent resource is published by ILADS here: http://www.ilads.org/files/ILADS_Guidelines.pdf.
CD-57 – Research breakthroughs by Dr
Joseph Burrascano and Dr. Ray Stricker, Directors of ILADS (International Lyme and Associated Diseases
Society) and long-time medical practitioners’, have shown a correlation between the CD-57 fighter cells and
Lyme disease. This
is how it works:
Chronic Lyme infections are known to suppress the immune
system. The Lyme spirochete can affect all major cell types of the immune
system, but it most clearly can impact a specific subset of the natural killer cells. This is called the CD-57
subset, and is part of the immune system which fights cancer. (Indeed the specialists who have been
studying this correlation fear that chronic Lyme may undermine the body’s cancer fighting
Just as in HIV
infection, which suppresses T-cell counts, Lyme suppresses Natural killer cell count such as CD57. As in HIV
infection, where abnormally low T-cell counts are routinely used as a marker of how active the infection is, in
Lyme disease we can use the CD-57 count to indicate
how active the Lyme infection is. When Lyme is active, the CD-57 count is low.
According to Dr. Burrascano and Dr.
Stricker, low CD57 occurs in chronic Lyme or when the disease has been active for over 1 year. Often reffered
to as the Stricker/Burrascano panel, the count reflects the degree of
* 0 - 60 indicates severe
* 60 - 100 the range for most chronic Lyme
* 100 - 200 may show improvement, still requires
* >200 is normal and safe to stop treatment without
If you want to use this test as part of your
health screen, Lyme screen or to track your progress here are his instructions and references
- Call LabCorp at 1-800-888-1113. Ask for
LabCorp Test # 505026, HNK (CD57) panel.
- As an alternative, contact Clinical Pathology
Labs at 1-800-595-1275. Ask for Test # 4885, CD57 Panel for Lyme disease.
Most commercial tests
designed to detect chronic infections are based on measuring your immune reaction—the presence of antibodies—to the
invading microbe. However, one of the primary cells that get infected with Lyme spirochetes are the white blood
cells themselves, which is a bit of a game-changer… because if your white blood cells are infected,
they lose the ability to produce antibodies.
That's why it is relatively common to get a negative test
Dr. Klinghardt refers to this as "the Lyme paradox," because in
order to diagnose Lyme disease properly with one of the accepted commercial tests, you have to first
treat the Lyme disease, in order
for your white blood cells to be able to mount an appropriate immune response. Only then can a lab test be used to
detect the presence of Lyme disease.
"An exception to that are the test based on direct
microscopy, where you're not depending on the immune responses for the patient," he explains.
However, this too has its drawbacks and difficulties. For
example, the FISH test for Babesia is done on blood. But Babesia lives in the central nervous system, joints, and
connective tissue. It doesn't live in your blood stream, at least not in significant amounts, so it can easily be
missed when looking at blood.
PCR - The polymerase chain reaction (PCR) is a technique widely used
biology, and is part of the Western Blot. However, there are many
other sensitive PCR tests which can be used to identify infectious diseases including Chlamydia Pneumoniae, Secondary Porphyria and
Immunoserology – Immunosciences Lab is
now providing a series of panels which appear to be more sensitive than the Western Blot, and test for more
sub-species antibodies and co-infections. Time will tell whether or not these panels will be helpful. For
more information see http://www.immuno-sci-lab.com/The%20Immunoserology%20of%20Lyme.pdf or http://www.immuno-sci-lab.com
Another new test
called VCS delivered by Dr. Shoemaker - Read about it here: http://www.chronicneurotoxins.com/learnmore/lymedisease.cfm
Important Notes on
- Fewer than 50%
of LD patients recall a tick bite or rash.
- Lyme disease is
greatly complicated by dozens of co-infections .
- Lyme spirochetes
can penetrate the central nervous system within 24 hours of tick bite according to Dr. Coyle at Stony Brook
- Sometimes people
don't get symptoms for years after they are bitten, so they don't realize they are
- A 1998 Swiss
study showed that only 12.5 percent of Bb positive patients had
If you are sick and treatments don't seem to help you
may have heavy metal toxicity. You can get a hair analysis done here: http://nutrignx.uckele.com/hair-mineral-analysis